Neuroleptic malignant syndrome (NMS) which can cause Dying. Tell you healthcare provider instantly In case you have any of the subsequent symptoms of NMS: substantial fever

The causal position of opioids within the medical syndrome of hypogonadism is unidentified as the different clinical, physical, Life style, and psychological stressors that may affect gonadal hormone amounts haven't been adequately controlled for in reports done to this point [see Adverse Reactions (six)].

If this SPL consists of inactivated NDCs stated through the FDA initiated compliance motion, They are going to be specified as such.

Tend not to utilize a home teaspoon to evaluate your medication. You might unintentionally acquire far too much. You may check with your pharmacist for the measuring product you need to use and how to evaluate the correct dose.

Because of the prospective for promethazine to reverse epinephrine’s vasopressor effect, epinephrine shouldn't be employed to take care of hypotension affiliated with promethazine overdose.

Given that recurrences of NMS are described with phenothiazines, stay away from utilization of promethazine HCl and codeine phosphate oral Remedy in patients with a record consistent with NMS.

A household teaspoon isn't an precise measuring system and could lead to overdosage [see Warnings and Safeguards (5.7)]. For prescriptions where by a measuring machine just isn't supplied, a pharmacist can provide an ideal measuring system and can offer Guidelines for measuring the proper dose. Don't overfill. Rinse the measuring product with drinking water immediately after Each individual use.

If concomitant use is warranted, diligently observe the patient, notably through procedure initiation. Discontinue promethazine HCl and codeine phosphate oral Alternative if serotonin syndrome is suspected.

Use caution When it comes to the usage of promethazine HCl and codeine phosphate oral Remedy in clients 65 a long time of age or older.

2)]. Instruct sufferers to get steps to store promethazine HCl and codeine phosphate oral solution securely also to adequately dispose of unused promethazine HCl and codeine phosphate oral solution in accordance with the area state recommendations and/or restrictions.

Marketing or giving away Promethazine with Codeine Oral Answer may possibly damage Other individuals, and it is from the law. Notify your healthcare supplier In case you have get more info at any time abused or been depending on alcohol, prescription medicines or Road drugs. Promethazine with Codeine Oral Resolution is not really for children below 6 a long time of age.

It's soluble in water and freely soluble in alcohol. The molecular fat is 320.88. Its molecular formulation is C17H20N2S•HCl, and it has the subsequent chemical composition.

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Impaired secretion from sweat glands subsequent toxic doses of medications with anticholinergic Uncomfortable side effects may predispose to hyperthermia.